New Step by Step Map For cees dekker
New Step by Step Map For cees dekker
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Rotary motion of DNA rotors on nanopores. Top rated row: Uncooked video in the Cy5 channel of every rotor. Center row: corresponding one-particle localization success of each ends with the DNA rotors. The posture of the present body is marked as orange and blue dots, and also the trajectory of the 10 frames ahead of The present body is demonstrated as stable strains.
It was only from the 1990s while, when nanotechnology had Innovative to a degree where by solitary molecules can be manipulated, that the initial experimental products began to seem.
‘It absolutely was basically a issue of choosing up a book on mobile biology and starting to read. I'd come from a world of extremely-significant vacuums, cryostats and quantum phenomena, and now I used to be working at home temperature with molecular biology kits.
Non-equilibrium folding of individual DNA molecules recaptured as much as one thousand instances within a sound point out nanopore
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Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en satisfied 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
Several linked developments adopted, where by our team founded distinctive transistor variants such as one-electron transistors at home temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled multiple transistors into small evidence-of-basic principle Digital circuits.
Finding out DNA loop extrusion by SMC proteins for chromosome architecture with solitary-molecule assays.
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Bulk-surface coupling identifies the mechanistic connection among Min-protein ceesdekker designs in vivo As well as in vitro
‘The concept there is such a issue for a commencing, a large bang, is presently a fascinating signpost to take into account that there was a creator. But much more typically, and on The idea of pure rationality, I also arrive at a Christian interpretation of actuality. An atheistic worldview is usually a naturalistic worldview: basically, there are actually only atoms and natural forces that we are able to measure.
Later on we spoke yet again briefly because Dekker felt that our discussion of his faith speedily turned purely philosophical, Whilst Additionally, it concretely aids him in his get the job done.
Visualization of unstained DNA nanostructures with advanced in-target transmission electron microscopy tactics
Solid-state nanopores have confirmed to become a astonishingly flexible probe for single-molecule Evaluation of DNA. I will describe some of our the latest conclusions – precisely DNA knots – and our endeavours to extend the abilities of reliable-condition nanopores even more, inside the path of single-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.